It's basically the same as your other question and its answer.
In all your examples here, at indicates an instantaneous event (not related to anything leading up to that event) had an effect; from indicates that the effect stemmed from an existing or long-standing condition.
I became hungry at the smell of the cookies.
The smell of the cookies reached you and you became hungry (instantaneous).
I was exhausted from working all day.
Working all day is a long-standing condition, not instantaneous.
I got excited at the sight of her face.
You saw her face and in an instant became excited.
The last one is more interesting:
I'm broke from having spent all my money at the bar.
Although you could have spent all your money in one transaction, so that you instantaneously became penniless, the use of the continuous having spent means that the state of penury has continued since that time. Consequently you use from.
You could even make a more ambiguous case with
I'm broke from all the expenditure I incurred.
But the same analysis applies: you incurred all the expenditure, and an hour later you had still incurred all that expenditure. It's not the same as suddenly seeing someone or smelling cookies.
Whether you use "in" or "to" depends on how you are using word that comes after it.
Interested in
When you use "interested in", you are usually talking about being interested in something (generally, a noun). For example, you can be interested in wine, or interested in cheese. Therefore, this sentence usually takes the form "[Someone] is interested in [something]."
There are times, however where the something you are interested in can be a verb. For example, you can be interested in swimming, or reading, or sleeping. In this case, the verb is acting like a noun. When a verb acts like a noun, it is called a gerund and almost always will end in "-ing".
Interested to
"Interested to" is a bit more complicated, because by itself it doesn't really make sense. The "to" is actually part of the verb that comes after it, like in "to read", "to see", or "to hear". This "to form" of the verb is known as the infinitive, and is used to add detail to (or modify) the word that comes before it.
This type of sentence usually takes the form of "[Someone] is interested [to do something]."
To really answer your question...
"Interested in" is used when what comes after it is a noun, or a verb acting like a noun (known as a gerund).
"Interested to" is used when what comes after it is a verb in its "to form" (known as an infinitive).
"I am interested in starting my career in your company" is the preferred construction. While "I am interested to start my career in your company" may be technically correct, you should not use it because people generally don't use "interested" with "to start". A more commonly accepted way to say it while still using the "to" would be "I am excited to start my career in your company".
Hope this helps, and good luck with your new career! :)
Best Answer
Not unique to the verb "to be beset", in general the two particles "by" and "with" imply different things. Consider the difference between these two requests:
By implies that you simply stand in the same physical space that she does. But with implies that you and she are standing together. To stand with someone connects the two of you much more than just to stand by them.
(That being said, the idiom "to stand by" can have several other meanings, which you have to determine from context. English is complicated.)
In the same way there's a subtle difference in the nuance between beset with and beset by. "With" suggests that the difficulties were connected to her career in some way -- that she ran into many problems as a consequence of the job. "By" suggests the difficulties were disconnected from her career, that they were not necessarily related to the job.