Learn English – Usage of ‘increase in’ and ‘increase of’

differenceword-choiceword-in-context

People with A exhibited a significant increase in proteins A, B and C.

XYZ is an event resulting in the decrease in protein C.

A is increased in people with PQR. This increase of (in) A is particularly significant.

From 1, 2, 3 and numerous other pages on this topic I was led to understand that sentences 1 and 2 would use the preposition 'in' instead of 'of'. But in sentence 3, since the stress is more on the 'increase' and not the 'amount', would we use of or in?

When I read 'increase of A' as a single 'entity' it sounds right. But since the word 'amount' or 'level' is implied, 'in' also sounds like it fits. In fact, the more I think about it, the more confused I get. Can someone please help?

Best Answer

The best I can tell you is that in is correct while of seams to be wrong.

Cambridge explains the use of "increase of" as a noun here: Nouns and prepositions from English Grammar Today

  • There has been an increase of 200,000 in the city’s population in the last ten years.
    (Of is used before numbers and quantities after increase/decrease/growth; in is used before the thing affected by the change.)
    Not: … an increase of the city’s population …

"an increase in" indicates growth of something that gets bigger in number or volume. (Longman Dictionary)

Based on what is known I can assume that a possible correct structure of the 3rd sentence using of can be the following:

  • A is increased in people with PQR. This *increase in people of A * is particularly significant.

You could restructure it and drop the of (in) A part to stay clear of unnecessary problems:

  • A is increased in people with PQR. This increase is particularly significant.