I saw the image below:
It's a reference to Beyonce (how you can see at the title here), her song is called Run The World (Girls).
Inside the context of the song. How about this substitution?
"Who order/boss the world? Girls"
Does run mean this? and Why was this word picked and not others?
And if you know, other use for run. Not like run in a race/the run actividade. Other uses and meanings, not the most common.
Best Answer
In your usage
means to control, organize, and coordinate the operations of an entity. It is usually used to describe
Your example is saying that the world is controlled by girls.