Learn English – What does “…,what foul dust floated in the wake of his dreams that…” mean

sentence-structure

I came across this famous sentence in the 4th paragraph of the 1st Chapter of The Great Gatsby.
The original sentence is here.

It's what preyed on Gatsby,what foul dust floated in the wake of his
dreams that temporarily closed out my interest in the abortive sorrows
and short-winded elations of men.

Why should the author use the second 'what' instead of "that".

And why should there lack a comma between 'his dreams' and 'that',like this.

It's what preyed on Gatsby,what foul dust floated in the wake of his
dreams,that
temporarily closed out my interest in the abortive sorrows
and short-winded elations of men.

The grammatical structure of the whole sentence confuses me a lot.

Best Answer

what also is a kind of emphatic.

"What big eyes you have, grandmother!" said Little Red Riding Hood.

what foul dust ...

emphasizes foul. The dust is very foul. It is so foul.

Consider this syntactic analogue:

Reporter: Tell me, Little Red Riding Hood, when did you become suspicious?
Little Red: Well, grannie looked especially hairy, and she was drooling more than usual, but it's what the look on her face was telling me, what big eyes she had, that really tipped me off.

In that usage what in what big eyes she had is not unlike emphatic/exclamatory "How":

How right you are!

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