Do from is an ‘Indianism’, so use of this phrase must be referred to speakers of that dialect.
In Standard English† we use at with the verb do; the preposition phrase names the place where the work was performed:
I did my doctorate at the University of Wisconsin.
He did an internship at Microsoft.
We use from in this context with receive; the preposition phrase names the entity which conferred the gift:
I received my doctorate from the University of Wisconsin.
In ordinary speech, however, we use the verb get, which may take either preposition phrase (though at is probably more common)
I got my bachelors at Vanderbilt.
I got my bachelors from Vanderbilt.
With do we use at;
In a question, no preposition at all is needed, whichever verb you use:
Where did you do your bachelors?
Where did you get your bachelors?
Where did you receive your bachelors?
†By “Standard English” I mean English usage which will pass unnoticed with any educated native speaker—appropriate to its register and not dialectal, foreign, antiquated, or precious.
The following informal mini-conversation occurs regularly in English:
I'd like to talk to you.
-- About what?
Any grammatical rule that would simply preclude the use of "About what" is a prescriptive rule. A descriptive rule would say, "The idiomatic way to tell someone, rather impatiently and brusquely, that they are not making themselves clear, is to ask What are you talking about?"
About what are you speaking? is "incorrect" insofar as it departs from idiomatic usage. Do you understand how that could be considered a far greater infraction than a violation of some prescriptive rule that has no basis in the spoken tongue?
Best Answer
If you want to know the name of the destination, for example "London", you ask
If you want to know the geographical location of the destination, (south-east England), you would ask
You might also use where to ask for directions to a place:
When asking about somebody's destination, you probably just want the name, in which case what is the right question-word.