At first none of the examples sounded good to my ear, but after I looked it up it seems that the 2nd and the 3rd are correct.
Many discuss the topic that whether medicine has true benefit on our society.
Whether is a subordinating conjunction. That is also a conjunction. Pilling up conjunctions one after another does not serve a purpose, and it is grammatically incorrect. Both of these conjunctions can be used to introduce a noun clause, but in your example the noun clause is derived form a yes/no question:
Does medicine have true benefit on our society?
Therefore you should use whether (that is used for noun clauses derived from statements).
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Many discuss the topic of whether medicine has true benefit on our society.
Google books shows evidence of "... of whether..." construction usage, e.g. in: "...the question of whether the pure self can be conceived of in unity with a living organism." At the same time
LDOCE gives examples of the construction "topic of". Since these two were my main concerns, the sentence should be correct.
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Many discuss the topic on whether medicine has true benefit on our society.
Again, there is evidence of usage of the phrase:
topic on whether, although there are only 68 hits, which would indicate that this phrase is used rarely.
Finally, Many question whether medicine brings a true benefit to the society would be my personal preference, but there are many ways to phrase this thought.
in return implies an exchange: You give me a ride to the event, and in return I'll cook a dinner for you.
in turn implies a sequence: Each player chooses a card in turn = The players take turns choosing a card.
in turn is correct here because the sentence describes a sequence (you give money, and then the school gives money) without exchange (the school does nothing to help the donor).
This is not to say that return is never appropriate in similar contexts. You pledge a dollar a month, and in return you get quality entertainment : here each party provides value to the other. Neither action must precede the other, so in turn would not fit.
Best Answer
The above sentence is wrong. You could say something like this,
Your second sentence is technically correct.
Using many or lots of requires a plural noun, therefore, "car" would never be correct, only "cars". And lots of is usually considered the more informal of the two – suitable for everyday conversation, but less likely to be found in a news article or technical paper.