Learn English – To “sheet home”

Yes, it makes the most sense. But, for one reason or another, the written version doesn't tend to bother with any punctuation at all. The closest thing I can find to a definitive answer comes from the apparent source of this phrase. I don't know for certain, but I think it is extremely likely that this common phrase came from the song of the same name. As you can see in the link, the punctuation in the song's title is either "Home! Sweet home!" or "Home, sweet home". So, the way you want to parse the phrase at least agrees with the creator's intent.

Previous answers suggested that

This example ought to strike home for you

means "This example should be understood by you" or "You should immediately understand this." It's possible that's what the writer meant, but if so, the writer hasn't phrased the sentence well. It's unlikely an informed native speaker would say such a thing with such a meaning.

The fact that ngrams for strike home for you shows no usage of the phrase reinforces how unlikely it is to occur, regardless of meaning; but note that the sentence could arise naturally in dialog like

Here's another good anecdote to include in your speech. This example ought to strike home for you.

In this case, someone is telling you that including a certain anecdote in a speech will serve well to get your message across to the audience.