Learn English – Why does to “take a powder” mean to run away or to leave

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From Flappers to Rappers: American youth slang by Dr. Thomas Dalzell cites "take a powder" as a 1930s expression meaning to run away or to leave. Does anyone have any ideas why taking a powder would mean running away or leaving?

Best Answer

The phrase take a powder meaning to "scram, vanish," is probably from the 20's; it was a common phrase as a doctor's instruction, so perhaps from the notion of taking a laxative medicine or a sleeping powder, with the result that one has to leave in a hurry (or, on another guess, from a magician's magical powder, which made things disappear). Powder blue (1650s) was smelt used in laundering; as a color name from 1894.

(The Word Detective)