So far, the tree seems rather underwhelming, especially the low-tier skills like Myelin, More Pep, Strength of 5 gorillas, etc.
Evil Enchantress apparently doesn't affect shock, fire and acid direct damage; it only buffs the status effects which is pretty pointless when slagging an enemy does 3X damage.
Shock storm doesn't sound useful as most enemies won't be bunched up enough.
On the other hand, the damage buffs from Wires Don't Talk and Interspersed Outburst look very useful. Make it Sparkle also apparently gives Deathtrap massive additional damage of up to 3X.
Is it worthwhile to spec into this tree just for the end-tier perks?
Best Answer
I have a Mechromancer character focusing on the 'Best Friends Forever' and the 'Little Big Trouble' skill trees (no Anarchy from 'Ordered Chaos') that I've been playing from TVHM to UVHM with UVH Upgrade Pack Two. As long as you have gear that will supplement Gaige's Little Big Trouble skills, you should be able to do fine on UVHM.
The most important skill in the Little Big Trouble skill tree is probably 'Wires Don't Talk' (increases all Shock and Electrocute Damage that you inflict). Due to that, I use gear that focuses on taking advantage of that skill.
Instead of More Pep, focus your points into another skill. More Pep's description is misleading, as described here.
Although, if you have a class mod that gives a bonus to More Pep, like Zapper or Legendary Catalyst, you might want to assign at least one point to the skill to get the bonuses given by that class mod.
LBT's The Stare is pretty weak (damage does not scale well) in UVHM. It also has bugs detailed here. It's pretty much a waste of a skill point. BFF's Explosive Clap seems to scale just fine in UVHM.
Gear that helps take advantage of Little Big Trouble skills:
Class Mods
Relics
An Elemental Relic (common) or a Bone of the Ancients (e-tech) that increases shock damage. The Bone of the Ancients also increases the Action Skill recharge rate, which can allow you to summon Deathtrap sooner.
Grenade Mods
Quoting Borderlands wiki:
This is mostly for slagging and for helping to heal with the Rubi. I opt to go with the Magic Missile if I am playing solo or if my co-op allies don't have much slagging capabilities. Otherwise, using a shock damage-dealing grenade mod is better.
Shock-only weapons
Elemental weapons that have shock versions
FFYL weapon, or area-clearing weapons
Shield
Black Hole (legendary) - quoting Borderlands Wiki:
The Bee (legendary amplify shield) - High amp shot damage, 0 amp shot drain. Lowered shield capacity. Increased shield recharge rate. Increased recharge delay.
This increases your weapons' damage at the cost of lower defensive capability. If you find that your Mechromancer's weapons' damage are lacking, you might want to use this shield. Works best with high fire rate weapons like the Shredifier and the Avenger. The Best Friends Forever skill tree's 'Fancy Mathematics' or 'Unstoppable Force' skills, or Ordered Chaos' Blood Soaked Shields skill will help keep this shield at full capacity.