Borderlands – What Borderlands 2 DLC is required to get 100% achievements

Experience & drops

Is experience gain individual, divided/split between players, or duplicated for each additional co-op player?

Each player gets the same experience. It is not split between them (like credits), but everyone gets the same amount (like ammo).

Do you get experience for others' work when you aren't in the same area of the map?

You have to be relatively near an enemy kill (but not that close) to get the XP. (I think.) But quest experience is given no matter who turns in the quest and no matter how far away they are.

Do all players get the same quest rewards?

All players get the same rewards, with the exception if the quest gives different guns per class or random guns. If it's a single item, it will simply drop into your inventory if you weren't the one to turn it in. If there is a choice of items, everyone will get the mission accept dialog to choose their reward individually.

How are experience, difficulty, and item/money drops affected for each additional co-op player?

I don't have exact stats, but there becomes more XP/items/cash and increased difficulty for each additional player.

Does the area difficulty scale to only the host's level, or does it accommodate/average difficulty between all players?

Host level, just like Borderlands 1. (You can twink low characters this way, as long as they don't get themselves killed everyone 10 seconds, I guess.)

Large level differences

Some games have disincentives when characters with large level differentials play together—is that the case in Borderlands 2?

I haven't researched this, but I think the mechanic is similar to the way Borderlands 1 worked: meaning the XP is shared (not split) no matter your level.

Are higher-level characters' stats adversely affected when joining a lower-level character's game? Or vice versa (boosting a lower-level character using a higher-level character's game)? Are experience gain or money/item drops diminished/impaired with large level differences? If so, what are the specifics?

It doesn't appear to alter the play stats or drops for differing levels. Basically, the host determines the level of enemies and drops, with number of co-op players increasing difficulty of enemies and amounts of enemies and item drops. (Though this isn't confirmed yet.)

TL;DR: On Normal, Scarlett's and Torgue's campaigns are supposed to be taken alongside the main quest, at any point since level 15. Hammerlock's and Tina's - after the main quest. On TVHM and UVHM - any campaign at any point.

Campaign DLCs scale to player's level when you first visit them, but with restrictions in Normal and TVHM. These are:

• Normal:
  • Captain Scarlett and her Pirate's Booty - levels 15 to 30.
  • Mr. Torgue's Campaign of Carnage - levels 15 to 30.
  • Sir Hammerlock's Big Game Hunt - levels 30 to 35.
  • Tiny Tina's Assault on Dragon Keep - levels 30 to 35.
• True Vault Hunter Mode: all DLC scales up to level 50.

Upper bounds is what I observe when returning my level 50 from TVHM. Lower bounds are what I see when jumping there with a level 8 character.

Big Game Hunt and Dragon Keep are the ones definitely designed to be taken after the main quest - other two are actually a breeze if you are level 33-34 after the main quest, and especially when you complete them at 36-38.

Side note: Mr. Torgue's Campaign of Carnage is NOT similar to Mad Moxxi's Underdome Riot - it is not a ladder of lots of rounds on a few arenas. It is what Underdome should have been - a full-sized quest line built around a tournament and several arena (and non-arena) battles (and non-battles).