The Binding of Isaac – Challenge Room Locked Even with Full Health

the-binding-of-isaac

I thought these opened if you have full health. I actually had full + 2 blue hearts before dropping a bomb on myself before taking the screenshot.

But even here I have full health… right?

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Best Answer

This is a boss challenge room, not a regular challenge room. You can tell there is a difference because on your minimap, there is a bit of blood on the sword and the skull above the door.

In order to enter, you must have one heart or less remaining (not including the blue hearts)

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