I have the Ehwaz rune. If I go into boss rush and take an item, can I use the rune to escape into the womb?
What if I had had "We Need To Go Deeper"?
Create a trapdoor in the boss rush room
the-binding-of-isaac-rebirth
Related Solutions
You need to beat Mom in The Depths / Necropolis in less than 20 minutes from the start of the run. Boss Rush will always appear if you do.
Note that it unlocks a different item/achievement for each character you beat Boss Rush with.
If you enter a seed, you will not be able to earn achievements or unlock items during that run in most cases but some seeds such as "qwop qwop" will still enable achievements while being a consistent seed. There is also no donation machine in the shop (but shop upgrades from previous runs still make more items available).
This is shown by the no achievement icon:
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- How does the damage resistance on Hush work, and how can you overcome it
Best Answer
Yes you can, with both the rune of Ehwaz and We Need to Go Deeper! The two items are fuctionally identical and they both work in the Boss Rush room. Keep in mind anyway that there is a not so low chance (~10%) of getting a Crawl Space instead of a passage to the next level when using these items.
A better way to be sure of getting out of the Boss Rush room is to use a teleporting item; this has also the added bonus of giving you a chance to get into the I AM ERROR room.