Diablo – Is your dodge / block chance reduced to zero if you have your back turned on an enethe? (ala WoW)

My findings have been interesting. It seems to be affected by how far it is from you and whether you are indoors.

If you are within about 1 and 1/2 to 2 screens' distance away from it when you are outdoors, then it dissipates in 60 seconds. This distance factor seems to be a lot smaller when you are indoors.

If you give sufficient distance, then it seems to last for a long time, as long as 50 minutes in one instance before disappearing.

Globes do not disappear when you exit the dungeon that you are currently in (either by portaling or exiting the current dungeon) and return later. They do disappear if you quit your current session, however.

I am going to stop testing as I doubt anyone would wait for more than 50 minutes to go back to a mere health globe. Boss fights last longer, but since most boss fights are fought in a constrained area, it's best to use the health orbs within a minute of them appearing as you are unlikely to get beyond two screens from them.

The party members don't actually have to be that close at all. The orbs that are displayed will apply health to everyone when the orb is picked up by anyone in the vicinity. This is probably why the required amount for this achievement is ridiculously high. This thread has a similar discussion.

05/17/12 - Last night my girlfriend and I did a little bit of testing, and we found that even someone standing pretty far off of the minimap view can still get the globe heal. I believe the shrine buff range is the same as health globes.

As far as the actual distance from the player is concerned it might be pretty hard to test.