Diablo – What are the differences between you and your clone

Much like World of Warcraft's launcher, "Playable" means the launcher has downloaded sufficient game code and initial media for you to launch the game and start playing it.

Unlike "available" where you run into "loading walls" where the game client struggles to keep up with downloading media necessary for you to play, "playable" means it has downloaded enough data for you to play without hitting any "loading walls".

Setup (Red): Core game content is being prepared. You cannot enter the game at this time.

Available (Yellow): Major game content is not completely applied. You can play, but your game experience will not be ideal.

Playable (Green): Final game content is almost complete. You may experience a few issues with playing at this stage.

The "Playable" includes high resolution textures and other low priority flair:

Q. How is data assigned to each stage?

A. Data is assigned to each stage based on the relative need for that data. Red is required to get into the game, Yellow is data needed for baseline gameplay, and Green is for variants of base game data (higher-resolution graphics, alternate sounds, other flavor data). [1]

Therefore, "optimal" means it has completed downloading all available content and will not impact your play experience with background downloads.

(Information is from World of Warcraft's launcher, which uses the same technology)

There is no need to actually click on the waypoint -- simply moving close to it is enough to activate it. This is a large visual and audio effect with pulses of blue light and sound, so it's very easy to tell when you have successfully activated a waypoint.

In multiplayer, you can teleport to any other player, so even if activating waypoints doesn't unlock them for all active players, all you need to do is teleport to your friend to immediately unlock the waypoint yourself.