Diablo III has two achievements that involve fighting bosses in nothing but your skivvies: Naked Lust and The Hero's New Clothes.
Obviously, clothes are kinda important.
Which class is best at slaying monsters in the nude? If you're seeking to complete this achievement in multiplayer, does everyone have to strip down, or just you?
And perhaps most importantly, do weapons count, or are we going to be punching Diablo to death?
Best Answer
I can't see any requirement to do this solo, nor that all your party members have to be naked as well.
In which case it would be simple: find a friend (or two or three), join up, and let them kill the boss with their gear. Probably you will die during the fight, but that won't stop you from scoring achievements.
I haven't tried this out yet, so this is pure speculation.
Update: yx. has tried it, and confirms it works (see comments). Thanks!