Donation Method - Ask a bot for a Spare Key!
There is a Steam Community bot that people donate extra DotA 2 keys to. You can add the bot as a friend and send him the private message "give dota" to get a DotA 2 key sent to you. You can donate any extra keys you end up with afterwards.
New Method - Buy the access to Dota 2 Beta
Valve gives now the possibility to buy directly an early access bundle through Dota 2 Store. The bundle contains the beta access key and some collectibles.
Old method - Join contests/giveaways
Beta Giveaway Contests (by Dota 2 communities)
One legal and legit way, is to participate to one of many contests available and hope to win. The official community of Dota 2 is PlayDota. I suggest you to register to to that site, because since the launch of Dota 2 Beta it was the main beta key distributor, through random beta keys giveaway (hundreds if not thousands key already distributed).
There are many other places around to check and it has no much sense list all sites here. Just check PlayDota forum and Dota 2 Reddit Channel, that are the two main Dota 2 international community sites at the moment. If a new giveway starts, it is usually advertised there.
SteamGifts is also an interesting community driven gift website (that support Steam logon) that often has Dota 2 keys.
Beta Tester Selection (by Valve)
If you don't have time, skill or attitude for a contest, you can try to install Steam and fill this survey.
It is an hardware survey followed by a simple questionnaire that will be used by Valve to target potential beta testers. Identified subjects will receive the beta access and 2 additional keys to invite some friends.
Other sources
Be aware of scammers sites or people that try to sell you fake keys, there are many around. Also buying valid keys infringe Steam rules, so just avoid it.
Update as of 18/1/2013
The options menu has been changed to make it easier to find the control rebinding for items. I have taken a new screenshot - simply click on steps 1 through 4 from anywhere in the game client to open up the menu and rebind your item hotkeys.
Note: this part of the answer is outdated, but I left it alone for now. If it's appropriate to delete it, mods are welcome to do so.
You can change the key bindings for both abilities and items by clicking their icons underneath the list of controls in the options menu. Below is a screenshot of the controls menu, you can see that I reassigned my items to numbers 1-4 and my extra mouse buttons.
It is not immediately apparent that these buttons which look like the ingame HUD are actually additional key binding options, but each one that is labelled can be changed.
It's also highly recommended that you rebind at least a few control group keys to something else, but it's rare that you will need all 6 control groups in a normal game. I chose F1-F3, but you can use whatever you like.
Best Answer
Combo usually stands for a combination of certain actions you do in certain order and granting you extra bonus for that.
I don't think that's what you have in mind. You are probably asking about putting certain actions into Queue - so that they are executed in certain order after each other.
I've played DotA + DOTA2 for long time, but currently I'm having long break, anyway when I played it was possible to put certain actions(I'm not sure if you can include spells in this queue, it was mostly used for walking in certain path/circles) into queue while holding SHIFT:
Example:
You want to walk certain way in woods, place a ward somewhere and go back. All you have to do is to HOLD SHIFT + click on some spots on the way where you wanna go, click on your ward HOLD SHIFT + place ward on the spot, HOLD SHIFT + click on place where you wanna go back to.
Now you release your SHIFT and your hero should be already on it's way to the spot, place ward and come back.
If I remember how this worked ;).