There's a PhD there, tantalizingly close to me, but just out of reach, blocked by those un-explodable blocks. How do I get to it?! (I've also encountered this set-up with another item).
How to get around black, square blocks
the-binding-of-isaac-rebirth
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Best Answer
You need to have an item that grants flight.
The list of items which grant permanent flight from the original game is:
There are probably several more in Rebirth.