Spoiler Alert…
(For a 7 month old game.)
In the sense that the minimum required runs to beat Mum's heart is 2:
- Beat Mum – unlocks womb.
- Beat Mum's heart.
The following hand waving occurs:
- You get the required deal with the angel/devil every time.
- You win every run.
Best Answer
The absolute minimum run involves the following:
The minimum run that requires as little luck as possible is: