Prevent unwanted items from appearing more than once in the same playthrough

the-binding-of-isaac

It happens every time! I go to the item room and find Teleport. I don't need Teleport, so I leave it. Then the next item I find is another Teleport! This will happen either in the challenge room on the same level or in the next item room. I thought I made it clear that I don't want Teleport. Is there any way I can prevent this from happening?

Note that this happens with unwanted items besides Teleport.

Best Answer

The "drops" are completely random. There is no way you can force an item to NOT drop, but you can mitigate your chances of getting a duplicate:

  • unlock everything you can. Characters' primary and secondary secret items, secret bosses, basically you have to play A LOT. Having to choose from a pool of 20 items is different from having to choose between 130.

  • unlock the D6 by:

    beating the Womb with ??? (that is unlocked by beating the game 10 times)

This item lets you re-roll your unwanted items and with some clever combinations and tricks, grants you almost any item you want.

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