In the present hub, there's a computer to play again Desmond's Missions.
But in the ending of the game, an event makes that hub becomes inaccessible in the end-game (spoilers!).
So, is it possible to replay Desmond's missions after completing the main game?
Best Answer
No, you cannot play Desmond's missions after completing the main game. You can however start a new game and play the missions on there.