What are the differences between the Console and PC versions of Cities Skylines

The DS version's main feature is a few extra playable characters with special abilities. The Wikipedia article covers most of the functional differences.

However, I would like to bring attention to the main difference in my head: the DS controls are horrible. Since the DS doesn't have an analog stick, you are forced to use either the DPad or the stylus. Both controls are clunkier and more annoying than their 64 counterparts.

I loved the 64 version and got every star in it, and really wanted to play it again with new characters. Unfortunately, the DS controls made me unable to stand playing the DS version for more than a few levels in. It would be nice if they would rereleased the rerelease on the Wii instead so I have some chance of ever completing it. However, if you play it on a 3DS, you can use the circle pad in place of the DPad, which fixes all of those problems. On 3DS, the DS version controls just fine.

The Xbox 360 version is different in that it features Kinect support. Here's an excerpt from the Destructoid review detailing the Kinect functionality:

Using Microsoft's camera accessory with the game is totally optional and serves to allow most of the game's basic commands to be given by voice. Kinect can be used to issue commands to squad members, activate special abilities, and change weapons, removing the need to open the game's power wheel, pausing the game and interrupting the flow of combat. Spoken instructions also extend to making dialog choices, opening doors, examining objects and pretty much anything else one would just press the 'A' button to do in a passive manner.

The marketing push for Mass Effect 3 states that the game is "better with Kinect," and it's hard not to agree. Voice recognition is very accurate, usually able to pick up commands even when speech is rushed. It's not perfect and does occasionally, rarely, fail to recognize a command but the system proves impressive nonetheless and it's easy to completely dispense with the power wheel altogether after giving it a little test.