Deus Ex – What’s the Difference Between Difficulty Settings?

deus-ex

Deus Ex's difficulty settings:

Difficulty selection screen

Considering the game's pedigree, I assume that higher settings do something in addition to boosting damage levels.

Best Answer

From the game's manual, third page (manual.pdf, included in the GOG version):

Combat Difficulty Level
When you start a new game of Deus Ex, the first thing you have to do is select the Combat Difficulty Level for your new game. There are four settings — Easy, Medium, Hard and Realistic. At higher difficulty levels you will take significantly more damage in combat. There are no other differences between difficulty levels. Once you select a difficulty level, you cannot change it without starting a new game.