In the case of, for example, someone else's life, you can either interfere in or with. The former is critical of the fact that you meddled at all. The latter is critical of the results of your meddling.
OP's definition of interfere in is correct - it means to get involved (usually, in matters that others think don't concern you).
To interfere with means to disrupt. Wave patterns, for example, can interfere with each other. This means they are mutually disruptive. Whilst it's true that interfering in someone else's affairs may be disruptive, it needn't be. But if you interfere with their affairs, you're definitely having a bad influence.
There's also the idiomatic usage of a paedophile interfering with a victim, which normally refers specifically to touching a child's genitals. I think in this case the thing being disrupted is the child's (future) sexual identity, but most of us would prefer not to dwell on the exact meaning there.
above at a high level ORIGIN Old English abufan (as an adverb), from a- ‘on’ + bufan (from bi ‘by’ + ufan ‘above’).
on physically in contact with (but also at a high level) ORIGIN Old English on, an, of Germanic origin; related to Dutch aan and German an, from an Indo-European root shared by Greek ana .
over at a high level same as above) or beyond (ORIGIN Old English ofer, of Germanic origin; related to Dutch over and German über, from an Indo-European word (originally a comparative of the element represented by -ove in above) which is also the base of Latin super and Greek huper .
on top of this is showing or identify that something is highest in the order of other things.
on top of 1 on the highest point or uppermost surface of: a town perched on top of a hill. • so as to cover; over: trays stacked one on top of another. • in close proximity to: we all lived on top of each other. 2 in command or control of: he couldn't get on top of his work. 3 in addition to: on top of everything else, he's a brilliant linguist.
(same Apple dictionary source)
Could over be similar to sopra? in application rather than meaning? overuse, overcoat, overseen, overhead, overhaul, overhand, overflow
There seems to be an English obsession (historical) with this desire of knowing where something is in relation to other things. Think on the reason why this and that code for proximity. Why is that important? short answer, we don't know.
etymology from Apple dictionary (Version 2.2.3 (118.5). Holmes (2001:329 -An Introduction to Sociolinguistics) raises this question on this v that and proximity...and why it seems important to code for it.
Best Answer
From ODO:
Live by allows the description of the means of subsistence (such as selling cars).
Live on is followed by what you have to live, not what you do.
So...