Diablo – Any tips for beating Malthael as a Wizard on high difficulty levels

Your new question is fairly dependent on a lot of factors, but you want to start you build by looking at a combination of Ray of Frost (either Snow Blast or Cold Blood). Snow Blast is technically our highest DPS, but it takes time for it to ramp up. If you are doing hit and run, then Cold Blood will serve you better and leave you more mana to work with.

Magic Missile with Charged Blast is going to be your best single target Primary unless you are trying to trigger a proc of some sort. If you are, then Electrocute is were you want to look for that. A good primary is important to keeping the damage up while you regen mana.

For raw damage increase, Force Weapon is an obvious buff worth taking. Sparkflint will increase both your attacks and provide shots of its own.

Hydra is probably the best spell for adding additional single target damage for little mana. The other Force and Conjuration spells are geared more towards AoE. Conflagration will cause the Hydra to give you an additional 10% boost to your damage.

Slow time can be used to boost damage in several ways in addition to providing some defense. Stretch time will provide a nice 10% increase to attack speed.

Arcane Dynamo, Conflagration, and Glass Cannon are going to be the passives you want to look at first.

So to sum it up, assuming single target with no worries about survival here is a good start:

Ray of Frost (Snow Blast or Cold Blood), Magic Missile (Charged Blast), Magic Weapon (Force Weapon), Familiar (Sparkflint), Slow Time (Stretch Time), Hydra, Arcane Dynamo, Conflagration, Glass Cannon

This is a hit and run build for solo wizard (lvl 58)

LC.Magic Missile | Seeker
(you don't have time in difficult situations to target the mobs :P)
RC.Arcane Orb | Tap the Source
(Decent splash damage)

1. Teleport | Reversal
   (You have a second chance to get yourself behind the mobs with reversal but be careful not to get in the middle of the fight)
2. Blizzard | Snowbound
   (cast Blizzard in front of you and run back so that mobs get showered)
3. Energy Armor | Force Armor
   (the rune does the trick! real life savior!)
4. Mirror Image | Mimics (Get the mobs destructed while you hit them from afar)

P1.Blur (self explanatory)
P2.Cold Blooded (bizzed mobs get more damage)
P3.Galvanizing Ward or Arcane Dynamo

http://eu.battle.net/d3/en/calculator/wizard#acQlOP!aWf!cYbbYc

Cast blizzard fall back hit with missiles and orbs. When they get too close teleport or mirror image to distract them. I am usually the only one to be left alive with this strategy in multiplayer games.