How many Opportunity Attacks (OA) does a PC get per round?
Example: if multiple foes go by a PC engaged in combat, and leaves their weapon reach, does the PC get an OA against each creature that goes by it?
Moving Around Other Creatures
If you leave a hostile creature’s reach during your move, you provoke
an opportunity attack …(Basic Rules p. 71:)
Opportunity Attack
You can make an opportunity attack when a hostile creature that you
can see moves out of your reach. (Basic Rules p. 73)
Best Answer
You only get ONE reaction between the start of your turn and the start of your next turn.
An Opportunity Attack is considered a Reaction (PHB pp195)
The Rules on Reactions are as follows (PHB pp190)
To clarify for you and your players: not only do you only get one attempt at an Opportunity Attack with your reaction, but it also means that you have spent your reaction. That means other movement that might trigger an Opportunity Attack for you would not because you no longer have your reaction; and other spells/abilities/etc that utilize a reaction (like Shield, Featherfall, Counterspell) would also no longer be an option as you have used your reaction.
What is a round?
Although initiative is ordered from highest to lowest, that isn't what the technical round is for your character. A round is from the start of your turn to the start of your next turn.
From Jeremy Crawford on Twitter (unofficially)